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  "assumptions": [
    "Independent Poisson counts within each four-cell interaction; no temporal overdispersion adjustment",
    "Published person-years treated as fixed",
    "Missing older postvaccine cells are omitted, not zero-filled"
  ],
  "limitations": [
    "Contrasts share references and populations; not independent studies",
    "Separate Holm families: 24 descriptive ratios and 8 direct interactions",
    "No adjustment for exact attained age, calendar time or confounding",
    "Sex interaction is not a vaccine-by-vaccine interaction",
    "Nonsignificant sex differences do not establish equivalence"
  ]
}